Cut and paste this URL to share the unmodified register and value:
https://regviz.com/r/STMicroelectronics/STM32U599/DBGMCU/APB1HFZR#0x0
Debug MCU APB1H peripheral freeze register
I2C4 stop in debug
LPTIM2 stop in debug
https://github.com/cmsis-svd/cmsis-svd-data